In a reassuring twist for coffee lovers, a recent study suggests that drinking three cups of coffee daily, equating to 200-300 mg of caffeine, may contribute to better cardiovascular health outcomes. According to Dr. Chaofu Ke, the lead author from Suzhou Medical College in China, this consumption level could help reduce the risk of developing cardiometabolic multimorbidity (CM) in individuals who currently have no cardiometabolic conditions.
So, what exactly is cardiometabolic multimorbidity? It refers to the simultaneous occurrence of two or more cardiometabolic diseases—a situation akin to a domino effect, where one health issue triggers others. As populations age, CM is becoming a significant concern for public health experts.
The study, titled “Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity,” was published in The Journal of Clinical Endocrinology & Metabolism. It found nonlinear inverse associations between coffee, tea, and caffeine intake and the risk of new-onset CM. Individuals consuming moderate amounts of coffee or caffeine exhibited the lowest risks for developing CM compared to non-consumers or those taking less than 100 mg of caffeine daily, with hazard ratios indicating a significant protective effect.
Furthermore, the study revealed that moderate coffee or caffeine intake was inversely associated with nearly all stages of CM development, including transitions from a disease-free state to single cardiometabolic diseases, and eventually to CM itself. Researchers identified 80 to 97 metabolites linked to coffee, tea, or caffeine intake that may contribute to this protective effect.
The findings suggest that habitual consumption of coffee or caffeine, particularly at moderate levels, could play a crucial role in reducing the risk of new-onset CM. However, researchers advocate for further studies to validate the metabolic biomarkers involved in the relationship between coffee, tea, caffeine, and CM.
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